cees dekker - An Overview
cees dekker - An Overview
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Rotary movement of DNA rotors on nanopores. Best row: Uncooked video clip of the Cy5 channel of every rotor. Middle row: corresponding solitary-particle localization outcomes of both of those ends of the DNA rotors. The posture of the current body is marked as orange and blue dots, as well as the trajectory of The ten frames just before The existing frame is revealed as sound strains.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
‘It absolutely was basically a make a difference of picking up a reserve on mobile biology and starting to browse. I'd come from a world of extremely-substantial vacuums, cryostats and quantum phenomena, and now I was Doing the job at place temperature with molecular biology kits.
Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2010, produced a different way (‘wedging transfer’) to govern nanostructures; first report of DNA translocation via graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into strong-point out nanopores
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
MATLAB codes for info processing are available at . Julia codes useful for numerical simulation can be found at .
Flow-driven rotary motors including windmills and h2o wheels travel functional processes in human Culture. While samples of this kind of rotary motors also attribute prominently in mobile biology, their artificial design within the nanoscale has remained demanding. Below we reveal flow-pushed rotary movement of the self-structured DNA nanostructure that may be docked on to a nanopore in a skinny solid-state membrane. An elastic DNA bundle self-assembles right into a chiral conformation on phoretic docking on to the good-point out nanopore, and subsequently shows a sustained unidirectional rotary movement of up to twenty rev s−one.
The rotors harness Vitality from the nanoscale drinking water and ion circulation that's created by a static chemical or electrochemical likely gradient inside the nanopore, that are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological ailments, suggesting approaches to constructing Electricity-transducing motors at nanoscale interfaces.
Bulk-surface coupling identifies the mechanistic connection among Min-protein designs in vivo As well as in vitro
‘The concept that There's such a issue to be a beginning, an enormous bang, is already an interesting signpost to take into consideration that there was a creator. But extra usually, and on The idea of pure rationality, I also arrive at a Christian interpretation of fact. An atheistic worldview is often a naturalistic worldview: essentially, you'll find only atoms and natural forces that we can easily evaluate.
2006, to start with demonstration of molecular sorting within a lab over a chip using biomotors; discovery of nanobubbles in sound-condition nanopores; and to start with estimate of electrokinetic Power conversion in the nanofluidic channel
Developments in nanotechnology in the 1990s produced developing electronic gadgets from single molecules a chance. Cees Dekker recounts how his crew designed a area-temperature transistor determined by one carbon nanotube.
2004, ceesdekker.net discovery of recent physics in translocation of DNA by way of nanopores; very first experimental study of ions conduction in nanofluidic channels; initially electrochemistry with personal single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; initial electrical docking of microtubules on kinesin-coated nanostructures; to start with biophysics characterization on the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule study of DNA translocation by a restriction-modification enzyme.